The eukaryotic nucleus contains the information that is required to build a complex organism. This complexity is achieved by a highly coordinated interaction between the DNA and the proteins that reside in the nucleus. Whereas the nuclear DNA has been fully sequenced, our understanding of the nature and the dynamics of the proteins in the nucleus is still limited, both in terms of the structural organization of the nucleus and of the regulation of gene activity. The goal of this Lecture Course is to foster scientific exchange between scientists working on the nuclear proteome, the dynamic behavior of proteins in the nucleus and the integration and visualization of protein and DNA networks. This Course is unique in that it focuses on nuclear proteomics and data integration in order to enhance our understanding of the molecular mechanisms that mediate epigenetic processes.
There will be dedicated sessions on the proteomic analysis of histone modifications, defined chromosomal domains, functional proteomics together with sessions on quantitative proteomics, emerging technologies and bioinformatic analysis of large proteomic datasets and their visualization. The Course includes lectures by leading researchers in the field, two poster sessions, oral presentations by junior researchers selected from the abstracts, meet-the-experts sessions and a round table discussion on emerging concepts and future developments in the field. A major feature of the Course is the problem solving sessions, whereby participants can discuss specific issues or problems of their projects in a one-to-one private session with one of the expert speakers of the Course.
The Lecture Course will take place at the beautiful, beach-front Neptune Hotel Resort and Conference Center on the island of Kos in Greece. The five-star resort complex is spread on 150.000 m² of private grounds with a modern Conference Center, excellent accommodation and top-class facilities. The cosmopolitan island of Kos is a very popular holiday destination with magnificent beaches, lush interior and a picturesque main town. The International airport of Kos is connected via charter flights to many European cities as well as to Athens and other major cities in Greece. There are also daily sea connections by ferry with the port of Piraeus (Athens).